Bowls containing different supplement pills

Top 5 Weight Loss Supplements

What is a Weight Loss Supplement?

A combination of cutting calories and being physically active is an excellent way to lose weight. Making these lifestyle changes can be challenging and some individuals may choose to take a weight loss supplement to improve their results.

A weight loss supplement helps a person lose weight through one or more of the following methods:

  • Increasing metabolism, by speeding up calorie burning.
  • Reducing appetite, so a person eats fewer calories.
  • Limiting the absorption of specific nutrients like fat and sugar.

Many weight loss supplements are available by prescription, but many more are available over the counter. Knowing which supplements stand out above the rest can help narrow down a person’s weight loss options.

5 Best Weight Loss Supplements

Over-the-counter weight loss supplements are taken by mouth and are sold as health aids.
Many claim to boost metabolism, boost energy and build muscle. Choosing the right weight loss supplements takes some research and here are five of the best weight loss supplements out there.

1. Hydroxycut

Hydroxycut is a recognizable name in the weight loss industry, as it has been around for more than a decade. It’s one of the most popular weight loss aids in the world, with a variety of weight loss products under the Hydroxycut name.

With caffeine as one of its main ingredients, Hydroxycut curbs appetite and boosts energy. Hydroxycut includes green coffee extract, which research shows to be a more effective weight loss supplement than placebos.

It’s important to note that in 2004 and 2009, Hydroxycut was noted to cause cardiovascular risk and hepatotoxicity but has since changed their formulations.


  •  Major name in the weight loss market.
  • Positive track record for effectiveness.
  • Many Hydroxycut products to choose from.
  • An affordable weight loss supplement, costing only $22.


  • May cause anxiety and tremors.
  • Ingredient quantities are not listed.

2. Alli

The weight loss supplement Alli is sold over the counter and is often prescribed under the names Orlistat and Xenical. Alli works by breaking down the fat that your body consumes, limiting the calories obtained from fat.

Research showed that Alli/Orlistat taken for 12 months along with physical activity and dieting saw 2.9% more weight lost than those in a placebo control group.


  • Available over the counter and by prescription.
  • Prescription strength.
  • Positive track record for effectiveness.
  • Affordably priced, this weight loss supplement costs $40 for one bottle.


  • Side-effects include loose oily stools and flatulence.
  • May cause vitamin deficiencies of fat-soluble vitamins.

3. Meratrim

Newer to the market than Alli or Hydroxycut, Meratrim is an organic diet supplement that claims users can lose weight within the first two weeks. Meratrim is also rich in antioxidants and may help boost the immune system.

Individuals who have taken Meratrim have also seen improvements in their cholesterol levels.


  • Organic ingredients.
  • Includes antioxidants.
  • Free of stimulants like caffeine.
  • Affordably priced: this weight loss supplement costs $50 for one bottle.


  • Contains allergens, like rice hull.
  • May cause nausea and bloating.

4. PhenQ

As one of the most trusted brands in weight loss supplements, PhenQ comes with glowing consumer feedback. PhenQ approaches weight loss through multiple avenues, boosting metabolism, enhancing energy and limiting the digestive processing of fats and sugars.

Individuals who have taken PhenQ have few complaints about side-effects, unlike other weight loss supplements.


  • Considered safest on the market.
  • Vegan-friendly ingredients.
  • Multiple approaches to weight loss.


  • Contains stimulants.
  • Can only be purchased online.
  • Costs $69 for one bottle.

5. PrimeShred

PrimeShred is a weight loss supplement targeted toward people looking to build muscle. Ingredients are natural and the company claims their product will build muscle while encouraging fat loss.

Natural ingredients like cayenne pepper, green tea and caffeine boosts weight loss and increases metabolism. PrimeShred has limited research to back its effectiveness.


  • Natural ingredients.
  • Vegan-friendly ingredients.
  • No additives or artificial ingredients.
  • Affordably priced: this weight loss supplement costs $49 for one bottle.


  • Contains stimulants.
  • Can only be purchased online.

Taking Weight Loss Supplements Safely

Weight loss supplements work differently for each person. When considering taking a weight loss supplement, remember to consult with a medical professional for the best results.